U of A spinoff, U.S. firm merge to commercialize transplant technology

Bridge to Life commits US$10 million to clinical trial and commercial development of Tevosol Ex-Vivo Organ Support System

U of A spinoff, U.S. firm merge to commercialize transplant technologyUniversity of Alberta spinoff company Tevosol has merged with the U.S.-based medical technology company Bridge to Life, bringing its game-changing organ transplant devices a step closer to approval, manufacture and global distribution. While Tevosol will remain based in Edmonton, Bridge to Life has committed US$10 million to a multi-centre clinical trial and commercial development of Tevosol’s Ex-Vivo Organ Support…

Fat cells may influence how the body reacts to heart failure

Promising results in mice open door to new areas of research in treating patients

Fat cells may influence how the body reacts to heart failureResearchers have found that limiting the amount of fat the body releases into the bloodstream from fat cells during heart failure could help improve outcomes for patients. In a recent study published in the American Journal of Physiology, Jason Dyck, professor of pediatrics in the Faculty of Medicine & Dentistry and director of the University of Alberta’s Cardiovascular Research Centre, found…

Stents more effective for patients with stable high-risk heart disease

Location of blockages in a patient’s heart is a key consideration in selecting the right treatment

Stents more effective for patients with stable high-risk heart diseaseA new study by University of Alberta cardiologists at the Canadian VIGOUR Centre shows that a particular group of patients with stable ischemic heart disease have better outcomes with percutaneous coronary intervention (also called angioplasty with stent) or coronary artery bypass surgery and medication, versus conservative management with medication alone. In a study published in the Journal of the…

Potential new treatments for cardiovascular disease

Researchers have identified a new mechanism responsible for the buildup of plaque on artery walls

Potential new treatments for cardiovascular diseaseGlycomics researchers at the University of Alberta and CHU Sainte-Justine have reported a discovery that could lead to new treatments for cardiovascular disease. The researchers identified a new mechanism responsible for the buildup of plaque on artery walls, a process known as atherosclerosis. This plaque, made up of fats, cholesterol and other substances, can restrict…

Wear Red Day warns women about risks of heart attack and stroke

To be held on Feb. 13, its goal is to arm women with knowledge and questions to ask their doctors

Wear Red Day warns women about risks of heart attack and strokeDid you know that heart attack and stroke represent the leading cause of premature death for women in Canada? Or that Canadian women are five times more likely to die of heart disease than breast cancer? Or that 53 per cent of women who have heart attack symptoms go undiagnosed when they seek medical treatment?…

‘Five-minute rule’ for organ harvesting holds true for cardiac death

Study undertaken to build trust with the public in the organ donation and transplantation process

‘Five-minute rule’ for organ harvesting holds true for cardiac deathA Canadian-led research project has confirmed that it’s safe to procure organs for transplant from dying patients once the heart has stopped for a full five minutes, in newly published findings in the New England Journal of Medicine. The researchers monitored blood pressure and electrocardiographic (ECG) waveforms in 631 dying patients following the removal of life-supporting equipment…

FDA approves new cardiovascular drug based on study at U of A

Vericiguat, which was shown to reduce risk of cardiovascular death and heart failure, passes final regulatory hurdle in the United States

FDA approves new cardiovascular drug based on study at U of AThe U.S. Food and Drug Administration has approved the drug vericiguat for use in patients with heart failure. The drug – a first-of-its-kind, once-daily oral treatment for patients with worsening chronic heart failure – was approved in part thanks to the VICTORIA (Vericiguat Global Study In Subjects With Heart Failure With Reduced Ejection Fraction) clinical study…

Collaboration key to solving medicine’s thorniest problems

A focus on teamwork and patient needs has led to breakthroughs in the search for cancer therapies, antivirals and safer drugs

Collaboration key to solving medicine’s thorniest problemsKhaled Barakat was stars-truck the first time he met Michael Houghton in 2012. He knew the U of A virologist and director of the Li Ka Shing Applied Virology Institute was renowned for discovering the hepatitis C virus and was likely to win a Nobel Prize (which Houghton eventually did in 2020). Barakat, a PhD in biophysics, landed an…

Women face higher risk of death or heart failure following a heart attack: study

Gap is closing, but U of A researchers find women are still given fewer tests and medications, and are less likely to see a specialist

Women face higher risk of death or heart failure following a heart attack: studyWomen face a 20 per cent higher risk than men of dying or having heart failure during the five years following a heart attack, according to a new study from University of Alberta cardiology researchers. “The women were on average a decade older than men at the time of their first heart attack and they more…