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People with arthritis are more likely than others to use cannabis for pain, mood and sleep disorders, but few studies have examined whether the products effectively treat the disease.

But that is about to change.

An interdisciplinary team of researchers at the University of Alberta is developing a cannabis use decision tool for the estimated 20 percent of Canadians who live with arthritis.

Cheryl Sadowski

Cheryl Sadowski

“We don’t have the evidence to say this product is a good choice or not a good one based on your symptoms,” said Cheryl Sadowski, a professor in the Faculty of Pharmacy and Pharmaceutical Sciences at the U of A. Sadowski noticed many of her patients have started using cannabis on their own since it was legalized in Canada in 2018. Medicinal cannabis has been allowed since 2001.

“Both patients and health professionals need tools to make decisions about what is the safest, most appropriate and most affordable use,” said Sadowski, who provides care at the geriatric outpatient clinic at Edmonton’s Misericordia Community Hospital.

“We see a lot of cannabis use in patients who have so many questions,” said co-principal investigator Elaine Yacyshyn, professor in the Faculty of Medicine & Dentistry and rheumatologist at the University of Alberta Hospital. She points out that a major concern is that patients stop taking prescribed and proven medicines in favour of cannabis, despite the lack of evidence.

“The tool has to be patient-centric and focused on their needs, so that pharmacists and physicians and their patients can have an open discussion and make an educated decision about use,” said Yacyshyn.

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The project team also includes patients, a physiotherapist, nurses, epidemiologists, students and a health economist. They will investigate how widespread cannabis use is among arthritis patients in Alberta, develop the tool using the best evidence available, and then validate it with patients and healthcare professionals. Other partners include the Arthritis SocietyAlberta Health Services, the Institute of Health Economics and Strainprint, a Canadian medical cannabis data company that collects consumer information.

Yacyshyn and Sadowski encourage people with arthritis to talk openly about the potential risks and benefits of cannabis use with their healthcare team.

“Cannabis use is now part of your regular medication history,” Sadowski said. “We used to have to put it under the category of illicit use along with cocaine and excessive alcohol. Now it’s just part of a list – are you taking aspirin, are you using a laxative, are you using cannabis? Be transparent about exactly what you’re taking, why you’re taking it and how much.”

The two-year project is one of three U of A investigations funded by an Alberta Innovates initiative to address urgent clinical or policy knowledge gaps related to the efficacy and safety of cannabis in a real-world setting.

| By Gillian Rutherford

This article was submitted by the University of Alberta’s Folio online magazine. The University of Alberta is a Troy Media Editorial Content Provider Partner.

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