Common chemotherapy drug linked to hearing loss in children

Half of children with cancer being treated with cisplatin suffer irreversible hearing loss

Common chemotherapy drug linked to hearing loss in childrenA University of Alberta research lab has helped identify a genetic variant that increases the risk of hearing loss in children with cancer who are treated with the widely used drug cisplatin. Amit Bhavsar, assistant professor in the Department of Medical Microbiology & Immunology and Canada Research Chair in Functional Genomic Medicine, led the U…

Lean on family, community after heartbreaking losses

Januel Ibasco kept his goals in sight despite the deaths of his mother and grandmother, and was inspired to explore his Filipino roots

Lean on family, community after heartbreaking lossesThe traditional Indigenous game of Back Push sees two competitors seated on the ground back-to-back with their arms locked. The object is to stand up together but push your opponent out of a designated area. The goal of a children’s version of the contest is to simply communicate and lean on each other so that,…

Incidents of serious parasitic disease on the rise in Alberta

The province is now the North American hotspot for a rare, potentially fatal disease

Incidents of serious parasitic disease on the rise in AlbertaA rare parasitic infection imported from Europe continues to take root in Alberta. The province is now the North American hotspot for human alveolar echinococcosis (AE), which takes the form of a growth in the liver, causing serious and potentially deadly health complications. A recently published review of known AE cases in Alberta found 17 instances…

Next-generation genetic sequencing to detect pancreatic and biliary cancer

Nearly $1M awarded to seven new projects from U of A researchers focusing on cancer, pulmonary, diabetes and neurology research

Next-generation genetic sequencing to detect pancreatic and biliary cancerSeven new University of Alberta research projects focusing on cancer, pulmonary disease, diabetes and neurology are the latest recipients of funding from the 2020 Kaye Competition. The annual competition supports individuals and collaborative, interdisciplinary and multidisciplinary teams in the pursuit of research, innovation and quality-improvement programs and projects that seek to establish new approaches to patient…

Hearing loss caused by common childhood cancer drug targeted

Research may eliminate the toxic side-effect of cispaltin in childhood cancer survivors

Hearing loss caused by common childhood cancer drug targetedUniversity of Alberta scientists have identified a receptor in cells that could be key to preventing permanent hearing loss in childhood cancer survivors being treated with the drug cisplatin. The researchers believe that, by inhibiting the receptor, they may be able to eliminate toxic side-effects from the drug that cause the hearing loss. Cisplatin is…

Unique cardiac rehabilitation program gives cancer patients hope

Helps cancer patients who also face heart damage due to their treatment

Unique cardiac rehabilitation program gives cancer patients hopeAsk Paul Guenard how he’s doing, and he’ll tell you, “Not bad for a guy who’s supposed to be dead!” While he laughs as he says it, Guenard did indeed face death six years ago when he underwent a stem cell transplant to treat mantle cell lymphoma. Afterwards, he said, he felt so weak he…

Marker may predict response to cancer immunotherapy

Abundance of protein galectin-9 in cancer patients is associated with poor response to immunotherapy

Marker may predict response to cancer immunotherapyUniversity of Alberta researchers have uncovered a link between the expression of the protein galectin-9 (gal-9) and whether a cancer patient will benefit from immunotherapy. The discovery could help inform physicians about which patients will likely respond to immunotherapy and lead to better treatment options. Immunotherapy or biological therapy is the treatment of disease by…

3-D bioprinting successfully used to create nose cartilage

Searching for a better solution to a clinical problem facing many patients with skin cancer

A team of University of Alberta researchers has discovered a way to use 3-D bioprinting technology to create custom-shaped cartilage for use in surgical procedures. The work aims to make it easier for surgeons to safely restore the features of skin cancer patients living with nasal cartilage defects after surgery. The researchers used a specially…

Nanomedicine used to provide better outcomes during chemotherapy

Nanomedicine used to provide better outcomes during chemotherapyA University of Alberta researcher is using nanotechnology to improve the effectiveness of chemotherapy treatments for cancer patients and reduce their side effects. Afsaneh Lavasanifar is a professor in the University of Alberta’s Faculty of Pharmacy & Pharmaceutical Sciences and an adjunct professor in the Department of Chemical and Medical Engineering. Her lab develops precision health solutions through nanomedicine,…

Innovative cancer therapy uses immune system to attack tumours

Re-engineers your immune system to target and attack cancer growing in your body

Innovative cancer therapy uses immune system to attack tumoursImagine if you could re-engineer your immune system to target and attack cancer growing in your body. A new clinical trial led by a clinician researcher at the University of Alberta is doing just that. Michael Chu, an assistant professor of oncology in the Faculty of Medicine & Dentistry, is leading a project to manufacture and…
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